Trimethoprim is a synthetic antibacterial agent belonging to the diaminopyrimidine class.Many formulations combine trimethoprim with sulfamethoxazole (e.g., Bactrim, Septra) to enhance their antibacterial effect.
Treatment of urinary tract infections (UTIs)
Treatment of acute exacerbations of chronic bronchitis
Treatment of traveler's diarrhea caused by susceptible strains of Escherichia coli
Treatment of Pneumocystis jirovecii pneumonia (PCP), often in combination with other medications
Treatment of skin and soft tissue infections
Bacstol 200mg Tab (Trimethoprim) inhibits bacterial dihydrofolate reductase, a crucial enzyme in the synthesis of folic acid. Folic acid is essential for bacterial DNA synthesis and growth. By blocking this enzyme, trimethoprim prevents bacterial replication and leads to bacterial death. When combined with sulfamethoxazole, a synergistic effect is achieved, resulting in enhanced antibacterial activity.
Store at room temperature, away from direct sunlight and moisture. Keep out of reach of children. Discard any unused medication after the expiration date.
Dosage varies depending on the infection being treated and the patient's condition. Always follow your doctor's prescription.
Medication is typically taken orally with or without food.
The duration of treatment varies based on the specific infection, but it usually lasts several days to a few weeks.
Nausea
Vomiting
Diarrhea
Abdominal pain
Rash
Itching
Headache
Dizziness
Alcohol consumption may increase the risk of side effects. Consult your doctor.
Trimethoprim may cause dizziness or drowsiness. Avoid driving or operating machinery if affected.
Use during pregnancy and breastfeeding should be carefully evaluated by a doctor due to potential risks to the fetus or infant.
Dosage adjustments are necessary for children based on weight and age. Follow your doctor's instructions.
Trimethoprim is primarily excreted through the kidneys. Kidney impairment may necessitate dosage adjustment to prevent drug accumulation.
Liver function should be monitored, especially in patients with pre-existing liver conditions.
Your doctor or pharmacist
The product monograph provided with your medication
Reputable medical websites such as those of national health organizations
