Zaporil 50mg Tab

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Composition

Clozapine (50mg)

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About Zaporil 50mg Tab

Zaporil 50mg Tab (Clozapine) is a powerful antipsychotic medication primarily used for treatment-resistant schizophrenia. It carries significant side effects, most notably the risk of agranulocytosis, requiring regular blood monitoring. It's crucial to follow your doctor's instructions meticulously regarding dosage and to report any unusual symptoms immediately. Alcohol consumption, driving, and operating machinery should be approached cautiously while taking clozapine.

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Ingredients

Directions for Use

How Drug Works

Storage & Handling

Drug Dosage

Side Effects

Safety Consideration or Warnings

References

Ingredients of Zaporil 50mg Tab

Clozapine

Is the active ingredient.

Direction for Use of Zaporil 50mg Tab

Treatmentresistant schizophrenia

Schizophrenia where other antipsychotics have been ineffective or poorly tolerated.

How Zaporil 50mg Tab Works

Zaporil 50mg Tab (Clozapine) is an atypical antipsychotic that works by blocking dopamine and serotonin receptors in the brain. This helps to reduce the positive symptoms (such as hallucinations and delusions) and negative symptoms (such as flat affect and social withdrawal) of schizophrenia.

Storage and Handling of Zaporil 50mg Tab

Store at room temperature, away from moisture and direct sunlight. Keep out of reach of children. Discard any unused medication as directed by your pharmacist.

Dosage of Zaporil 50mg Tab

Dosage is determined by your doctor and adjusted based on your individual response and tolerance.

It is usually started at a low dose and gradually increased.

It is typically taken orally, as a tablet.

Dosage may vary from 12.5 mg to 900 mg per day or more, divided into two or more doses.

Side effects of Zaporil 50mg Tab

Orthostatic hypotension (low blood pressure upon standing)

Agranulocytosis (a serious decrease in white blood cells requiring regular blood monitoring)

Sedation or drowsiness

Dizziness

Weight gain

Increased appetite

Constipation

Dry mouth

Blurred vision

Seizures (rare but possible)

Myocarditis (inflammation of the heart muscle)

Safety Consideration or Warnings

Alcohol Consumption

Alcohol should be avoided or severely limited as it can increase the sedative effects of clozapine.

While Driving or operating Machinery

Avoid driving or operating machinery until you know how clozapine affects you, as it can cause drowsiness and dizziness.

Pregnant & Breastfeeding Women

Clozapine should only be used during pregnancy or breastfeeding if the benefits outweigh the risks. Discuss this with your doctor.

Children

Clozapine is not typically used in children.

Kidney

Dose adjustment may be necessary for patients with kidney impairment.

Liver

Dose adjustment may be necessary for patients with liver impairment.

References

Your prescribing physician's information

The official drug monograph from the FDA or equivalent regulatory body in your country.

Peer-reviewed medical journals and textbooks.

Last Updated On 14 Dec. 2025 | 07:17 PM (IST)

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